pentobarbital will lower the level or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Suggested atogepant dosage with concomitant use of sturdy or reasonable CYP3A4 inducers is 30 mg or 60 mg qDay.pentobarbital will decrease the extent or outcome of brexpiprazole by influencing hepatic/